The Logitech company sells a large range of both wired and wireless computer mice. Although different mice will have different buttons and features, the process for fixing them if they aren't working will be essentially the same for any model. There are several troubleshooting steps you can attempt on your own before having to contact Logitech for help.
Check to make sure that the Logitech mouse is plugged firmly into your computer's USB, or serial port if it is a wired mouse. Make sure that the receiver is plugged into the USB port on your computer and has a set of fully charged batteries inside if you have a wireless Logitech mouse.
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Make sure that there is no radio frequency interference in the room where your computer is located if you are using a wireless mouse. Remove any 2.4 GHz wireless phone lines, active Bluetooth devices or even microwave ovens in the room. Check the manual for your wireless mouse and make sure that you are not exceeding the maximum range that the mouse can be from the receiver.
Click on the "Start" button on the bottom task bar on your computer and then choose "Control Panel." Click on "Add or Remove Programs." Choose the option to remove the Logitech software if you installed any when you first got the mouse. Navigate your Web browser to the Logitech website (see Resources below). Access the "Downloads" page for the model of mouse that you have and then download the latest software available. Wait for the file to finish downloading and then double-click on it to install the program.
Navigate back to the Control Panel and then click on "Device Manager." Press the plus sign next to the heading for your mouse. Right-click on the name of your mouse and then choose "Properties." Click on the "Drivers" tab and then click on "Find Drivers." Choose the option to download a new driver if your current driver is out of date.
Pull the ball out of the top of the mouse if your Logitech mouse uses a track ball. Use a paper towel to clean out any dust particles and then put the ball back in. Flip your mouse over if it is not a track ball and check to see if it has screws holding the sensor in or if it simply has a sliding plastic piece. Slide the plastic piece in a circular pattern and then pull it off or use a screwdriver to remove the screws. Gently clean out the inside the mouse with a paper towel and then put the plastic cover back on. Attempt to use the mouse again and then contact Logitech's customer support if it sill isn't working.
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The radio frequency has to be calibrated between the receiver and the mouse if you are using a wireless mouse. You can reset the calibration by removing the batteries from the receiver and then putting them back in.