Apple no longer limits the number of iPods that can synchronize with a single iTunes account on one computer, which is good news for multiple-iPod families or for individuals who prefer to keep only their exercise music on an iPod Nano and the rest of their music on an iPod Touch.
Name each of the iPods differently.
Create a playlist specific to each iPhone in iTunes and fill it with music only for that specific phone. Create a separate designated folder or album for photos.
Sync each iPhone one at a time. When you connect each iPhone, iTunes recognizes the name and allows you to designate playlists and photo albums or folders specific to that iPhone. Choose the playlist you set up for the iPhone under the "Music" tab at the top of the iTunes main screen. Under the "Photos" tab, choose the specified album or folder.
Click the "Apply" button to apply the preferences and the "Sync" button to transfer the music and photos to the iPhone. When you are done setting up the first iPhone, eject it. Attach the second iPhone and repeat the procedure with the second phone's folder and playlist.
Sync separate sets of contacts by creating two groups of contacts in your address book on a Mac. Under the "Info" tab in iTunes, after selecting your iPhone icon, select which contact group syncs with that iPhone.