Your Twitter timeline can become an overwhelming place if you follow a lot of people. With the typical Twitter user tweeting several times per day, you can easily lose track of updates from your favorite Twitter users as you plough through hundreds of posts. That's why Twitter gives you the ability to group together users in separate lists. After configuring a list, you can filter the tweet stream by clicking the list name to ensure that you never miss updates from the Twitter users you care about most.
Launch a Web browser and log in to your Twitter account. Click the "Profile and Settings" button labeled with your profile image in the top menu bar.
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Select "Lists" from the pull-down menu and then click the "Create a new list" button.
Type the name and description of the list, select the privacy setting for the list and click "Save List."
Click the "Home" button and then "Followers" and "Following."
Click the gear icon in the profile pane for a user you would like to add to a saved list, then select "Add or remove from lists" and click the list to add that user to the list.
Repeat this process for each user you would like to add to the newly created list. You can also add Twitter users you do not follow to the list by visiting their Twitter profile and clicking the list icon.
Delete a list that you don't need any more by selecting "Lists" from your Twitter profile page. Click the list name, select the "Delete" button and then click "Yes" in the confirmation window.