One of the benefits to having McAfee security software on your computer is that it uses a convenient pop-up system to let you know about important security updates, as well as updates to the software itself. If you don't want to see these pop-ups any more, you will need to enable McAfee's "Gaming Mode". This mode suppresses pop-up notifications. While it is intended to only suppress pop-ups while you are playing a game, you can use enable this setting for as long as you want.
Double-click the McAfee "M" icon in your system tray to launch your McAfee dashboard.
Click on "Personal Firewall" and then select "Options". Then click on "Alert" settings. You will see a list of options pertaining to your pop-up settings.
Find the "Enable Gaming Mode" option and click on the checkbox next to it. Click "OK" to save the settings. All pop-up activity will cease.